Stuart Howes

Stuart Howes

Class of 2010
Undergraduate Institution: Worcester Polytechnic Institute
Major: Biomedical Engineering
Origin:
Dover, NH

Lab:
Eva Nogales

Location:
742 Stanley Hall

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Research
 
I work on understanding the role tubulin acetylation plays in the structure of microtubules and how proteins recognize this modification, which occurs in the lumen of the microtubule.
Publications
 
  • Ramey VH, Wong A, Fang J, Howes S, Barnes G, Nogales E. Subunit organization in the Dam1 kinetochore complex and its ring around microtubules. 2011. Mol Biol Cell. 22:4335-42.
  • Rissin DM, Fournier DR, Piech T, Kan CW, Campbell TG, Song L, Chang L, Rivnak AJ, Patel PP, Provuncher GK, Ferrell EP, Howes SC, Pink BA, Minnehan KA, Wilson DH, Duffy DC.  Simultaneous detection of single molecules and singulated ensembles of molecules enables immunoassays with broad dynamic range. 2011. Anal Chem. 86:2279-85
  • Rissin DM, Kan CW, Campbell TG, Howes SC, Fournier DR, Song L, Piech T, Patel PP, Chang L, Rivnak AJ, Ferrell EP, Randall JD, Provuncher GK, Walt DR, Duffy DC. Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. 2010. Nat Biotechnol. 28:595-99.

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