|
Joshua LevitzClass of 2009Undergraduate Institution: American University Major: Biology, Physics Origin: Sunnyvale, CA Lab: Udi Isacoff Location: 279 Life Sciences Addition |
Research |
I work on developing optical control of ion channels and G-protein coupled receptors. I use these optogenetic tools to probe receptor cooperativity and various forms of synaptic plasticity.
Publications |
Joshua Levitz, Carlos Pantoja, Benjamin Gaub, Harald Janovjak, Andreas Reiner, Adam Hoagland, David Schoppik, Brian Kane, Philipp Stawski, Alexander F. Schier, Dirk Trauner, Ehud Y. Isacoff. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 2013.
Guillaume Sandoz, Joshua Levitz, Richard Kramer, Ehud Y. Isacoff. Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in hippocampal GABAB signaling. Neuron. 2012. 74(6):1005-14
Luke H. Chao, Margaret M. Stratton, Il-Hyung Lee, Oren Rosenberg, Joshua Levitz, Daniel J. Mandell, Tanja Kortemme, Howard Schulman, John Kuriyan. A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme. Cell. 2011.146(5):732-45.
Guillaume Sandoz, Joshua Levitz, Richard Kramer, Ehud Y. Isacoff. Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in hippocampal GABAB signaling. Neuron. 2012. 74(6):1005-14
Luke H. Chao, Margaret M. Stratton, Il-Hyung Lee, Oren Rosenberg, Joshua Levitz, Daniel J. Mandell, Tanja Kortemme, Howard Schulman, John Kuriyan. A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme. Cell. 2011.146(5):732-45.
